Coupling of liquid chromatography with mass spectrometry by desorption electrospray ionization (DESI).
نویسندگان
چکیده
A liquid chromatography/mass spectrometry (LC/MS) method using desorption electrospray ionization (DESI) as a versatile interface has been established, which allows a wide range of elution flow rates, online derivatization via reactive DESI and further combination with electrochemistry.
منابع مشابه
Direct analysis of liquid samples by desorption electrospray ionization-mass spectrometry (DESI-MS).
Desorption electrospray ionization-mass spectrometry (DESI-MS) was evaluated for the direct analysis of liquid samples. Several interesting results were found. First, in contrast to the previous DESI analysis of dried solid samples that was limited to proteins with MW < or = 25 kDa (Anal. Chem. 2007, 79, 3514), bovine serum albumin (BSA, 66 kDa) was successfully ionized from solutions by DESI w...
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عنوان ژورنال:
- Chemical communications
دوره 47 14 شماره
صفحات -
تاریخ انتشار 2011